Capítulo 9: Nefrotoxicidad por fármacos

Autores/as

  • Marina Papaginovic Hospital Churruca Visca, Ciudad Autónoma de Buenos Aires, Argentina
  • Guillermo Rosa Diez Universidad de Buenos Aires, sede Hospital Italiano de Buenos Aires, Ciudad Autónoma de Buenos Aires, Argentina
  • Sonia Butto Hospital Churruca Visca, Ciudad Autónoma de Buenos Aires, Argentina
  • Claudio González Universidad Austral, Ciudad Autónoma de Buenos Aires, Argentina

DOI:

https://doi.org/10.47196/diab.v58i2Sup.792

Palabras clave:

nefrotoxicidad inducida por fármacos, enfermedad renal, diabetes mellitus

Resumen

La nefrotoxicidad inducida por fármacos, también denominada enfermedad renal inducida por fármacos (ERIF), afecta entre el 14% y el 26% de los pacientes adultos y a el 16% de los pacientes pediátricos. Sin embargo, la incidencia de ERIF puede llegar al 66%. Entre los adultos mayores la incidencia es mayor, puesto que estos se caracterizan por presentar múltiples enfermedades, la polifarmacia y, por lo tanto, están sujetos a procedimientos diagnósticos y terapéuticos que pueden dañar los riñones. La disfunción renal suele ser reversible al suspender el fármaco causante; sin embargo, puede producir daño estructural irreversible. La nefrotoxicidad se manifiesta en un amplio espectro, reflejando daño en diferentes segmentos de la nefrona, incluidos los segmentos glomerulares y tubulares.

Biografía del autor/a

Marina Papaginovic, Hospital Churruca Visca, Ciudad Autónoma de Buenos Aires, Argentina

Médica especialista en Medicina Interna y Nefrología

Guillermo Rosa Diez, Universidad de Buenos Aires, sede Hospital Italiano de Buenos Aires, Ciudad Autónoma de Buenos Aires, Argentina

Médico especialista en Nefrología y Medio Interno, Magíster en Efectividad Clínica (UBA), Doctor en Ciencias de la Salud (Universidad del Hospital Italiano de Buenos Aires), Director del Curso de especialista en Nefrología

Sonia Butto, Hospital Churruca Visca, Ciudad Autónoma de Buenos Aires, Argentina

Médica especialista en Medicina Interna y Nefrología

Claudio González, Universidad Austral, Ciudad Autónoma de Buenos Aires, Argentina

Profesor, Titular de Farmacología, Instituto Universitario Centro de Educación Médica e Investigaciones Clínicas "Norberto Quirno" (CEMIC), Director de la Maestría en Diabetes

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Publicado

02-05-2024

Cómo citar

Papaginovic, M., Diez, G. R., Butto, S., & González, C. (2024). Capítulo 9: Nefrotoxicidad por fármacos. Revista De La Sociedad Argentina De Diabetes, 58(2Sup), 54–62. https://doi.org/10.47196/diab.v58i2Sup.792

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