Diabetic kidney disease: definition, diagnosis, different progressive stages, classification
DOI:
https://doi.org/10.47196/diab.v51i3.103Keywords:
kidney disease, progression stages of glomerular filtration, albuminuria, classificationAbstract
Chronic kidney disease (CKD) is classified according to the cause, the stage of glomerular filtration and albuminuria. Diabetic kidney disease (DKD) according to the classification of glomerular filtration (GF) and the quantification of albuminuria. The kidney disease (KD) is defined with GF ≤60 mil/min, whereas renal insufficiency (RI) covers stages G3 onwards. The level of urinary albumin excretion, associated with the speed of glomerular filtration, sets the prognosis of chronic kidney disease. A significant percentage of patients (20 to 48%) present a reduction of the glomerular filtration rate without significant se albuminuria.
References
Fineberg D, Jandeleit-Dahm K, Cooper M. Diabetic ne- phropathy: diagnosis and treatment. Nat Rev Endocri- nol 2013; 9: 713-723.
National Kidney Foundation. KDIGO 2012 Clinical prac- tice guideline for the evaluation and management of chronic kidney disease. Kidney Int. Suppl 2013; 3:1-150.
Thorn LM, Gordin D, Harjutsalo V, et al. Presence and consequence of nonalbuminuric chronic kidney disea- se in patients with type 1 diabetes. Diabetes Care 2015; 38:2128-33.
Papadopoulou-Marketou N, Chrousos GP, Kanaka-Gan- tenbein C. Diabetic nephropathy in type 1 diabetes: a review of early natural history, pathogenesis and diag- nosis. Diabetes Metab Res Rev 2017; 33(2).
Huang M, Liang Q ,Li P, et al. Biomarkers for early diag- nosis of type 2 diabetic nephropathy: a study based on an integrated biomarker system. Mol. BioSyst 2013; 9(8):2134-41.
Papale M, Di Paolo S, Magistroni R, et al. Urine pro- teome analysis may allow noninvasive differential diagnosis of diabetic nephropathy. Diabetes Care 2010; 33(11):2409-15.
Zürbi P, Jerums G, Hovind P, et al. Urinary proteomics for early diagnosis in diabetic nephropathy. Diabetes 2012; 61(12):3304-13.
Laranjinha I, Matias P, Mateus S, et al. Diabetic kidney disease: is there a non- albuminuric phenotype in type 2 diabetic patients? Nefrología 2016; 36(5) 503-9.
Retnakaran R, Cull CA,Thorne KI, UKPDS Study Group. Risk factors for renal dysfunction in type 2 Diabetes. U.
K. Prospective Diabetes Study 74. Diabetes 2006; 55(6): 1832-9.
Tervaert TH, Mooyart AL, Amann K, et al. Pathologic classification of diabetic nephropathy. J Am Soc Ne- phrol 2010; 21(4): 556-63.
Chenyang Q, Xing M, Zhigang Z, Huijuan W. Classifica- tion and differential diagnosis of diabetic nephropaty. J Diab Res 2017: article ID 8637138, 7.
Downloads
Published
How to Cite
Issue
Section
License
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
Dirección Nacional de Derecho de Autor, Exp. N° 5.333.129. Instituto Nacional de la Propiedad Industrial, Marca «Revista de la Sociedad Argentina de Diabetes - Asociación Civil» N° de concesión 2.605.405 y N° de disposición 1.404/13.
La Revista de la SAD está licenciada bajo Licencia Creative Commons Atribución – No Comercial – Sin Obra Derivada 4.0 Internacional.
Por otra parte, la Revista SAD permite que los autores mantengan los derechos de autor sin restricciones.
