Comparison of the frequency of therapeutic target blood pressure between three studies and its association with the variables analyzed
DOI:
https://doi.org/10.47196/diab.v58i3.1140Keywords:
type 2 diabetes, blood pressure goals, associated factors, treatment, adherenceAbstract
Introduction: blood pressure (BP) control prevents the onset and progression of chronic complications of type 2 diabetes mellitus (DM2).
Objectives: to compare the frequency of BP in therapeutic target between three studies conducted in adults with DM2 in Argentina, and its association with the variables analyzed.
Materials and methods: cross-sectional, comparative design of three multicenter studies, which included adults with DM2 assisted by specialists in 2006-2011 and 2018. Target: BP <140-90 mmHg. The frequency of BP in target was compared in relation to the differences between the study populations, duration of DM2, chronic complications, treatment strategies, adherence and quality of life. Adherence and quality of life questionnaires were applied. History, clinical examination and laboratory tests were analyzed.
Results: of 4709 patients, 83% had arterial hypertension (HTN). The BP goal was achieved by 64.7%, 67.6% and 52.4% in 2006, 2011 and 2018 respectively (p<0.0001). Regarding the pharmacological treatment of HTN, without treatment: 3%, 2% and 6.5% (2006, 2011 and 2018; p=0.0001). The most commonly used antihypertensives in 2006, 2011 and 2018 were: ACEI decreasing (p=0.0001), followed by ARBs increasing (p=0.0001); Thiazides (p=0.0001) and atenolol (p=0.001) decreased, and carvedilol (p=0.0001) and amlodipine (p=0.013) increased. BP achievement was associated with lower body mass index (BMI) and waist circumference (p=0.0001), greater physical activity (p=0.0001), use of antihypertensives (p=0.0001), quarterly check-ups (p=0.0001), HbA1c <7% (p=0.0001), coronary heart disease (p=0.001) and having health insurance (p=0.001).
Conclusions: lower achievement of the therapeutic BP goal was associated with central obesity and nephropathy; the variables associated with greater achievement were: physical activity, taking antihypertensives, periodic check-ups and private health insurance.
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