Elevation of the neutrophil/lymphocyte ratio and its relationship to C-reactive protein in patients with type 2 diabetes mellitus

Authors

  • Adriana Pedreáñez Santana Faculty of Medicine, University of Zulia, Maracaibo, Venezuela
  • Jesús Mosquera-Sulbarán Faculty of Medicine, University of Zulia, Maracaibo, Venezuela
  • Jorge Robalino Institute of Gynecology and Osteoporosis (INGINOST), Riobamba, Ecuador
  • Diego Tene General Hospital of the Ecuadorian Institute of Social Security (IESS), Riobamba, Ecuador
  • Nelson Muñoz Faculty of Health Sciences, National University of Chimborazo, Riobamba, Ecuador

DOI:

https://doi.org/10.47196/diab.v55i3.474

Keywords:

diabetes, inflammation, neutrophil/lymphocyte ratio

Abstract

Diabetes mellitus (DM) is a metabolic disease characterized by hyperglycemia, which occurs as a consequence of defects in the action of insulin on its receptor, in insulin secretion, or in both. Chronic hyperglycemia is associated with long-term damage, dysfunction, and failure of different organs, especially eyes, kidneys, nerves, heart, and blood vessels. It is a disease that has reached epidemic proportions. The latest edition of the International Diabetes Federation (IDF) Atlas shows that 463 million adults are currently living with DM and it is estimated that there will be 578 million adults with DM by 2030 and 700 million by 2045. The prevalence of DM ( in adults aged 20-79 years) in Central and South America was 8.5% in 2019 and it is expected that by 2030 it will be 9.5 and 9.9% by 2045.

Author Biographies

Adriana Pedreáñez Santana, Faculty of Medicine, University of Zulia, Maracaibo, Venezuela

PhD in Immunology; Head of the Chair of Immunology

Jesús Mosquera-Sulbarán, Faculty of Medicine, University of Zulia, Maracaibo, Venezuela

Physician; Dr. in Medical Sciences

Jorge Robalino, Institute of Gynecology and Osteoporosis (INGINOST), Riobamba, Ecuador

Degree in Health Sciences and Clinical and Histopathological Laboratory

Diego Tene, General Hospital of the Ecuadorian Institute of Social Security (IESS), Riobamba, Ecuador

MSc Management in Health for Local Development

Nelson Muñoz, Faculty of Health Sciences, National University of Chimborazo, Riobamba, Ecuador

MSc in Bioanalysis and Laboratory Diagnosis

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Published

2021-09-01

How to Cite

Pedreáñez Santana, A., Mosquera-Sulbarán, J., Robalino, J., Tene, D., & Muñoz, N. (2021). Elevation of the neutrophil/lymphocyte ratio and its relationship to C-reactive protein in patients with type 2 diabetes mellitus. Journal of the Argentine Society of Diabetes, 55(3), 77–83. https://doi.org/10.47196/diab.v55i3.474