Conference of the Nephropathy Committee of the Argentine Society of Diabetes. Bariatric surgery update in a patient with diabetes and kidney disease. Part 2
DOI:
https://doi.org/10.47196/diab.v55i3.487Keywords:
obesity, diabetes, bariatric surgery, metabolic surgery, chronic kidney disease, focal and segmental glomerulopathyAbstract
The prevalence of obesity and diabetes mellitus are associated with the development of chronic kidney disease and its terminal stages. In individuals affected by obesity, a probably compensatory hyperfiltration mechanism occurs to satisfy the high metabolic demand associated with increased body weight; it is also associated with the presence and development of proteinuria in individuals without kidney disease. Histopathology shows obesity-related focal and segmental glomerulosclerosis in a setting of glomerulomegaly. Metabolic surgery is the most effective means of obtaining substantial and lasting weight loss. The superiority of surgery over medical treatment has been demonstrated only to achieve better glycemic control, as well as a reduction in cardiovascular risk factors. The mechanisms appear to extend beyond the magnitude of weight loss and include improvements in incretin profiles, insulin secretion, and insulin sensitivity.
The Nephropathy Committee of the Argentine Diabetes Society carried out this review on mechanisms involved in obesity as a cause of kidney disease or worsening of kidney disease due to diabetes, the mechanisms by which bariatric surgery would benefit patients with diabetes and kidney disease chronic and its terminal stages, the pre and post-surgical controls that should be performed by patients undergoing this type of surgery.
References
I. Kovesky CP, Furth SL, Zoccoli C. Obesity and kidney disease: hidden consequences of the epidemic. Canadian Journal of Kidney Health and Disease 2017; (4):1-10.
II. Organización Mundial de la Salud. 16 de febrero de 2018. Obesidad y sobrepeso.
III. Cuarta Encuesta Nacional de los Factores de Riesgo. Dirección Nacional de la Promoción de la Salud y control de Enfermedades Crónicas no Transmisibles. Principales resultados. 2018. Disponible en: https://bancos.salud.gob.ar/sites/default/files/2020-01/4ta-encuesta-nacional-factores-riesgo_2019_principales-resultados.pdf.
IV. Foster MC, Hwang SJ, Larson MG, et al. Overweight, obesity, and the development of stage 3 CKD: the Framingham Heart Study. Am J Kidney Dis 2008 Jul; 52(1):39-48.
V. Wang Y, Chen X, Song Y, et al. Association between obesity and kidney disease: a systematic review and meta-analysis. Kidney Int 2008 Jan; 73(1):19-33.
VI. Mathers CD, Loncar D. Projections of global mortality and burden of disease from 2002 to 2030.PLoS Med 2006; 3(11):e442.
VII. Subramanian SV, Perkins JM, Özaltin E, et al. Weight of nations: a socioeconomic analysis of women in low- to middle-income countries. Am J Clin Nutr 2011; 93(2):413-421.
VIII. Tsujimoto T, Sairenchi T, Iso H, et al. The dose-response relationship between body mass index and the risk of incident stage ≥3 chronic kidney disease in a general Japanese population: the Ibaraki prefectural health study (IPHS). J Epidemiol 2014; 24(6):444-451.
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2021 on behalf of the authors. Reproduction rights: Argentine Diabetes Society.
![Creative Commons License](http://i.creativecommons.org/l/by-nc-nd/4.0/88x31.png)
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
Dirección Nacional de Derecho de Autor, Exp. N° 5.333.129. Instituto Nacional de la Propiedad Industrial, Marca «Revista de la Sociedad Argentina de Diabetes - Asociación Civil» N° de concesión 2.605.405 y N° de disposición 1.404/13.
La Revista de la SAD está licenciada bajo Licencia Creative Commons Atribución – No Comercial – Sin Obra Derivada 4.0 Internacional.
Por otra parte, la Revista SAD permite que los autores mantengan los derechos de autor sin restricciones.