Report of high insulin requirements in pediatric critically ill patients with COVID-19. Experience with continuous remote glucose monitoring

Authors

  • Andrea Gabriela Krochik Prof. Dr. Juan P. Garrahan Hospital, Autonomous City of Buenos Aires, Argentina
  • Mariana Prieto Prof. Dr. Juan P. Garrahan Hospital, Autonomous City of Buenos Aires, Argentina
  • Carolina Martínez Mateu Prof. Dr. Juan P. Garrahan Hospital, Autonomous City of Buenos Aires, Argentina
  • Consuelo Barcala Prof. Dr. Juan P. Garrahan Hospital, Autonomous City of Buenos Aires, Argentina
  • Rosario Gallagher Prof. Dr. Juan P. Garrahan Hospital, Autonomous City of Buenos Aires, Argentina
  • Silvia Filippini Prof. Dr. Juan P. Garrahan Hospital, Autonomous City of Buenos Aires, Argentina
  • Delfina Arambarri Institute of Research in Electronics, Control and Signal Processing (LEICI), National University of La Plata, National Council for Scientific and Technical Research (CONICET), Province of Buenos Aires, Argentina
  • Leandro Mendoza Institute of Research in Electronics, Control and Signal Processing (LEICI), National University of La Plata, Province of Buenos Aires, Argentina
  • Nicolás Rosales Institute for Research in Electronics, Control and Signal Processing (LEICI), National University of La Plata, National Council for Scientific and Technical Research (CONICET), Province of Buenos Aires, Argentina
  • Hernán De Battista Institute for Research in Electronics, Control and Signal Processing (LEICI), National University of La Plata, National Council for Scientific and Technical Research (CONICET), Province of Buenos Aires, Argentina
  • Ricardo Sánchez Peña Technological Institute of Buenos Aires, National Council for Scientific and Technical Research (CONICET), Autonomous City of Buenos Aires, Argentina
  • Fabricio Garelli Institute for Research in Electronics, Control and Signal Processing (LEICI), National University of La Plata, National Council for Scientific and Technical Research (CONICET), Province of Buenos Aires, Argentina

DOI:

https://doi.org/10.47196/diab.v55i2.462

Keywords:

COVID-19, hyperglycemia, pediatric critical patient, remote glucose monitoring

Abstract

Critically ill patients with COVID-19 suffer from sustained hyperglycemia that is difficult to manage. Added to this is the challenge of minimizing exposure to contagion.

In this article we analyze the metabolic evolution of two pediatric patients with COVID-19 admitted to the intensive care unit (ICU) for COVID-19 patients at the Hospital “Prof. Dr. Juan P. Garrahan ”from the Autonomous City of Buenos Aires, Argentina, who required treatment with intravenous insulin and whose blood glucose was remotely monitored with the InsuMate® platform developed at the National University of La Plata.

The patients required insulin infusion rates in doses markedly higher than those of other critically ill patients, who were impressively related to the values of inflammation markers. The infusion could be adjusted with four daily glucose monitors and the metrics obtained with the glucose monitor. The use of the continuous remote glucose monitoring system made it possible to decrease the frequency of glycemic monitoring during treatment.

Author Biographies

Andrea Gabriela Krochik, Prof. Dr. Juan P. Garrahan Hospital, Autonomous City of Buenos Aires, Argentina

Pediatrician, specialist in Pediatric Nutrition; Head of Clinic of the Nutrition Service

Mariana Prieto, Prof. Dr. Juan P. Garrahan Hospital, Autonomous City of Buenos Aires, Argentina

Pediatrician Specialist in Pediatric Nutrition

Carolina Martínez Mateu, Prof. Dr. Juan P. Garrahan Hospital, Autonomous City of Buenos Aires, Argentina

Pediatrician Specialist in Pediatric Nutrition

Consuelo Barcala, Prof. Dr. Juan P. Garrahan Hospital, Autonomous City of Buenos Aires, Argentina

Pediatrician Specialist in Pediatric Nutrition

Rosario Gallagher, Prof. Dr. Juan P. Garrahan Hospital, Autonomous City of Buenos Aires, Argentina

Pediatrician, specialist in Pediatric Intensive Therapy

Silvia Filippini, Prof. Dr. Juan P. Garrahan Hospital, Autonomous City of Buenos Aires, Argentina

Pediatrician, specialist in Pediatric Intensive Therapy

Delfina Arambarri, Institute of Research in Electronics, Control and Signal Processing (LEICI), National University of La Plata, National Council for Scientific and Technical Research (CONICET), Province of Buenos Aires, Argentina

Computer Engineer, Applied Control Group, Institute of Research in Electronics, Control and Signal Processing (LEICI), National University of La Plata, National Council for Scientific and Technical Research (CONICET)

Leandro Mendoza, Institute of Research in Electronics, Control and Signal Processing (LEICI), National University of La Plata, Province of Buenos Aires, Argentina

Engineering Student

Nicolás Rosales, Institute for Research in Electronics, Control and Signal Processing (LEICI), National University of La Plata, National Council for Scientific and Technical Research (CONICET), Province of Buenos Aires, Argentina

Doctor of Engineering, Applied Control Group, Institute for Research in Electronics, Control and Signal Processing (LEICI), National University of La Plata, National Council for Scientific and Technical Research (CONICET)

Hernán De Battista, Institute for Research in Electronics, Control and Signal Processing (LEICI), National University of La Plata, National Council for Scientific and Technical Research (CONICET), Province of Buenos Aires, Argentina

Doctor of Engineering, Applied Control Group, Institute for Research in Electronics, Control and Signal Processing (LEICI), National University of La Plata, National Council for Scientific and Technical Research (CONICET)

Ricardo Sánchez Peña, Technological Institute of Buenos Aires, National Council for Scientific and Technical Research (CONICET), Autonomous City of Buenos Aires, Argentina

Doctor in Engineering

Fabricio Garelli, Institute for Research in Electronics, Control and Signal Processing (LEICI), National University of La Plata, National Council for Scientific and Technical Research (CONICET), Province of Buenos Aires, Argentina

Doctor of Engineering, Applied Control Group, Institute for Research in Electronics, Control and Signal Processing (LEICI), National University of La Plata, National Council for Scientific and Technical Research (CONICET)

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Published

2021-08-02

How to Cite

Krochik, A. G., Prieto, M., Martínez Mateu, C., Barcala, C., Gallagher, R., Filippini, S., Arambarri, D., Mendoza, L., Rosales, N., De Battista, H., Sánchez Peña, R., & Garelli, F. (2021). Report of high insulin requirements in pediatric critically ill patients with COVID-19. Experience with continuous remote glucose monitoring. Journal of the Argentine Society of Diabetes, 55(2). https://doi.org/10.47196/diab.v55i2.462

Issue

Section

Clinical cases

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