Association between uricemia and metabolic syndrome in a hospital center in Corrientes

Authors

  • Silvia Beatriz Gorbán de Lapertosa Faculty of Medicine, Northeast National University (UNNE), Corrientes, Argentina
  • Claudia Alejandra Miño Hospital Angela I. de Llano, School of Dentistry and School of Medicine, National University of the Northeast (UNNE), Corrientes, Argentina
  • Isabel Cristina Llanos Hospital Ángela I. de Llano, Faculty of Dentistry, Faculty of Medicine (UNNE), National Northeast University (UNNE), Corrientes, Argentina
  • Claudio Daniel González Faculty of Medicine, Austral University and Favaloro University. University Institute of the Center for Medical Education and Clinical Research "Norberto Quirno" (CEMIC), Autonomous City of Buenos Aires (CABA), Argentina

DOI:

https://doi.org/10.47196/diab.v56i3.524

Keywords:

metabolic syndrome, uric acid, hyperuricemia

Abstract

Introduction: in recent years, numerous scientific evidence suggest that hyperuricemia may play a role in the development of metabolic syndrome (MS). Some studies have explored the association between uricemia and the presence of MS. However, it remains unclear whether high uric acid levels are causally related to the development of MS. Moreover, there are few studies on the presence of metabolic syndrome and its relationship with uric acid (UA) levels in the city of Corrientes, Argentina.

Objectives: to determine the relationship between serum UA levels and the parameters that define MS in patients attending the outpatient clinic of Medical Clinic and General Medicine of the Ángela I. de Llano Hospital, Corrientes.

Material and methods: quantitative, descriptive, cross-sectional study. A questionnaire was applied to collect data such as age, sex, medications used, and smoking history. Participants' weight, height, waist circumference and body mass index were measured. Basal glucose, oral glucose tolerance curve, uric acid, triglycerides, HDL cholesterol, and systolic and diastolic blood pressure were determined. The presence of MS was defined according to the modified National Cholesterol Education Program-Adult Treatment Panel III (NCEP-ATPIII) criteria.

Results: a total of 435 patients over 18 years of age were included: 312 (72%) women and 123 (28) men. Fifty-eight percent of the population met the NCEP-ATP III criteria for MS (60% females and 52% males). Seventy-five percent of the population had hyperuricemia and MS. In this study the presence of MS was significantly associated with uricemia values OR:1.5 (95%CI:1.3-1.8). The association is statistically significant.

Conclusions: The results show that the increase in the frequency of the components of MS, goes in direct relation with the increase in serum UA levels and that the cut-off value for this association is 4 mg/dl. Hence the importance of considering the determination of serum UA levels as a possible predictor of MS.

Author Biographies

Silvia Beatriz Gorbán de Lapertosa, Faculty of Medicine, Northeast National University (UNNE), Corrientes, Argentina

Professor of Nutrition and Health Education, Bachelor's Degree in Kinesiology and Physiatry

 

Claudia Alejandra Miño, Hospital Angela I. de Llano, School of Dentistry and School of Medicine, National University of the Northeast (UNNE), Corrientes, Argentina

Biochemistry, Master in Research in Health Sciences; Head of Practical Work, Biochemistry subject

Isabel Cristina Llanos, Hospital Ángela I. de Llano, Faculty of Dentistry, Faculty of Medicine (UNNE), National Northeast University (UNNE), Corrientes, Argentina

Biochemistry, Master in Research in Health Sciences; Head of Practical Work, Biochemistry subject

Claudio Daniel González, Faculty of Medicine, Austral University and Favaloro University. University Institute of the Center for Medical Education and Clinical Research "Norberto Quirno" (CEMIC), Autonomous City of Buenos Aires (CABA), Argentina

Professor of Pharmacology

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Published

2022-12-01

How to Cite

Gorbán de Lapertosa, S. B., Miño, C. A., Llanos, I. C., & González, C. D. (2022). Association between uricemia and metabolic syndrome in a hospital center in Corrientes. Journal of the Argentine Society of Diabetes, 56(3), 83–92. https://doi.org/10.47196/diab.v56i3.524

Issue

Vol. 56 No. 3 (2022): September/December 2022

Section

Original article

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