Symposium 2: Should we treat neuropathy in T2DM differently?
DOI:
https://doi.org/10.47196/diab.v56i3Sup.493Keywords:
diabetes mellitus, neuropathyAbstract
Diabetic neuropathy (DN) belongs to the microvascular complications with a major impact on quality of life and on life expectancy. It is a neurodegenerative disorder that compromises both the somatic and autonomic peripheral nervous systems in the context of Diabetes Mellitus. DN is a very prevalent complication that can be present even in non diabetic dysglycemia stages and Metabolic Syndrome. It requires a sustained intervention, and prevention of its appearance must be attempted.
Regarding management, it is postulated that the optimization of glycemic control is effective as a therapeutic measure in people with T1Diabetes mainly, while the intervention must be multifactorial in patients with T2Diabetes. In this population, changes in lifestyle, with physical exercise and weight loss represent the bases of management for distal and symmetric diabetic polyneuropathy, which is the most frequent clinical form to observe in daily clinical practice. These changes should be implemented early in the course of the disease1.
References
I. Cernea S, Raz I. Diabetes: State-of-the-Art 100 years after the discovery of insulin. Special Issue. Edited by S. Polyzos and C. Mantzoros 2021; Vol. 123.
II. Feldman E, Callaghan B, Pop-Busui R, et al. Diabetic neuropathy. Nat Rev Dis Primer. 2019 Jun 13;5(1):42
III. Stino A, Smith A. Peripheral neuropathy in prediabetes and the metabolic syndrome. J Diabetes Investig 2017;Vol. 8,5.
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