Symposium 11: Obesity in adolescence
DOI:
https://doi.org/10.47196/diab.v56i3Sup.574Keywords:
diabetes mellitus, farmacologíaAbstract
Since the 1980s, the prevalence of overweight has increased in the general population and in patients with T1D.
Prevalence of obesity in diabetes1: SEARCH 34.7%, T1D ECXHANGE, 36%, DPV 15.3% and SWEET 29.6% and 34%.
Causes
• Eating habits with higher consumption of processed foods, refined sugars and saturated fats.
• Counting carbohydrates.
• More sedentary lifestyle
• Intensified treatment age-specific insulin resistance
Obesity contributes to insulitis and autoimmunity by secretion of chemokines from activated immune cells and B cells themselves in response to proinflammatory stimuli, promoting inflammation and B cell death.
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