Importancia del manejo de la glucosa postprandial en la diabetes tipo 2. Tratamiento y nuevas terapéuticas
DOI:
https://doi.org/10.47196/diab.v48i1.179Palabras clave:
diabetes tipo 2, glucemia postprandial y GLP-1Resumen
El óptimo control glucémico es importante para disminuir el riesgo de complicaciones crónicas en el paciente diabético. Sin embargo hay un alto porcentaje de pacientes tratados con insulina y/o agentes orales que no alcanza los objetivos, particularmente por elevación de la glucemia postprandial.
Tradicionalmente el manejo del paciente con diabetes tipo 2 ha focalizado la terapéutica en el control de la glucemia en ayuno, dado la alta correlación de la misma con la hemoglobina glicosilada. Actualmente hay extensa evidencia para afirmar que la glucemia postprandial cumpliría un rol fundamental en el sub-óptimo control glucémico, con las complicaciones que esto conlleva.
La homeostasis glucémica es compleja de lograr en pacientes con diabetes y la terapéutica debe estar orientada a restablecerla. El objetivo de esta revisión es destacar la importancia del manejo de la glucemia postprandial en diabetes tipo 2, establecer el tratamiento actual de la misma y evaluar cuáles serían las nuevas terapéuticas disponibles.
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