O13 Association of cardiometabolic markers and central obesity in normal and overweight or obese children

Authors

  • Valeria Hirschler Durand Hospital, Autonomous City of Buenos Aires, Argentina
  • Claudia Molinari University of Buenos Aires, Autonomous City of Buenos Aires, Argentina
  • Gustavo Maccallini Durand Hospital, Autonomous City of Buenos Aires, Argentina
  • Claudio Daniel González "Norberto Quirno" Center for Medical Education and Clinical Research (CEMIC), Autonomous City of Buenos Aires, Argentina

DOI:

https://doi.org/10.47196/diab.v54i3Sup.374

Keywords:

cardiometabolic markers, obesity, children

Abstract

Objective: To determine the association of cardiometabolic markers and central obesity
(OB) in four groups of school children: 1- normal weight with central OB 2- normal weight without central OB, 3- OW (overweight) / OB with central OB, and 4- OW / OB without central OB in a sample of school children.

Methods: A cross-sectional study was carried out in schoolchildren between November 2011 and 2013. Children's anthropometric measurements, blood pressure (BP) and serum levels of glucose, lipids and insulin were measured. Maternal BMI and waist circumference (WC) were evaluated. Children were classified as having OW (BMI = 85-
94th percentile) and OB (BMI> 95th percentile) according to the CDC. Central OB was classified as WC> 90th percentile.

Results: A total of 1,264 schoolchildren (624 F), mean age 9.5 ± 2.2 years old, were evaluated. The prevalence of OW/ OB was 32% (405) and that of central OB was 24.5% (310). The prevalence normal weight children without central OB was 64.3% (796), normal weight with central OB 5% (66), OW / OB without central OB 11% (137) and OW / OB with central OB 21% (265). Normal weight children with central OB had significantly
higher triglyceride levels than normal weight children without central OB (86 vs 70 mg / dL, respectively). Children with normal weight with central OB had significantly higher triglycerides (81 vs 77 mg / dL) and lower maternal BMI (24 vs 28 kg / m2) than OW / OB children but without central OB. Interestingly, normal weight children with central OB had lower BMI (19 vs 20 kg / m2) but significantly higher WC (73 vs 65 cm) than OW / OB children without central OB, suggesting that WC would be a better marker of cardiometabolic complications than BMI. Children with OW / OB with central OB had systolic (100 vs. 94 mmHg) and diastolic BP (61 vs. 58 mmHg), triglycerides (101.0 vs. 70.5 mg / dl), insulin (8.6 vs. 6, 1 IU / dL), triglycerides / HDL-C (2.6 vs 1.5) and nonHDL-C (100.5 vs 93.4 mg / dL) higher, while HDL-C (44, 0 vs 49.9 mg / dl) lower compared with children with OW / OB children without central OB. Multiple linear regression analysis showed that age, systolic BP, HDL-C, triglycerides, and maternal
WC were significantly associated with WC; adjusted for confounding variables (R2 =
0.50).

Conclusion: This study suggests that schoolchildren with normal weight or with OW / OB with central OB have higher levels of cardiometabolic markers compared with those
without central OB. Future longitudinal studies should be done to confirm these findings.

Author Biographies

Valeria Hirschler, Durand Hospital, Autonomous City of Buenos Aires, Argentina

Pediatrician, specialist in Nutrition and Diabetes

Claudia Molinari, University of Buenos Aires, Autonomous City of Buenos Aires, Argentina

Chair of Mathematics, Faculty of Pharmacy and Biochemistry

Gustavo Maccallini, Durand Hospital, Autonomous City of Buenos Aires, Argentina

Biochemist

Claudio Daniel González, "Norberto Quirno" Center for Medical Education and Clinical Research (CEMIC), Autonomous City of Buenos Aires, Argentina

Pharmacologist doctor; Advisor on the methodology of the clinical and epidemiological evidence qualification processes

Published

2023-01-10

How to Cite

Hirschler, V., Molinari, C., Maccallini, G., & González, C. D. (2023). O13 Association of cardiometabolic markers and central obesity in normal and overweight or obese children. Journal of the Argentine Society of Diabetes, 54(3Sup), 98–98. https://doi.org/10.47196/diab.v54i3Sup.374

Issue

Section

Selected articles. Oral presentations

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