CHAPTER 9: NEPHROTOXICITY BY DRUGS

Authors

  • Marina Papaginovic Churruca Visca Hospital, City of Buenos Aires, Argentina
  • Guillermo Rosa Diez University of Buenos Aires, Italian Hospital headquarters, City of Buenos Aires, Argentina
  • Sonia Butto Churruca Visca Hospital, City of Buenos Aires, Argentina
  • Claudio González Austral University, City of Buenos Aires, Argentina

DOI:

https://doi.org/10.47196/diab.v58i2Sup.792

Keywords:

drug-induced nephrotoxicity, renal disease, mellitus diabetes

Abstract

Drug-induced nephrotoxicity, also called drug-induced kidney disease (DKD), affects 14% to 26% of adult patients and 16% of pediatric patients. However, the incidence of ERIF can be as high as 66%. Among older adults, the incidence is higher, since they are characterized by multiple diseases, polypharmacy and, therefore, are subject to diagnostic and therapeutic procedures that can damage the kidneys. Renal dysfunction is usually reversible upon discontinuation of the offending drug; however, it can cause irreversible structural damage. Nephrotoxicity manifests itself in a broad spectrum, reflecting damage to different segments of the nephron, including the glomerular and tubular segments.

Author Biographies

Marina Papaginovic, Churruca Visca Hospital, City of Buenos Aires, Argentina

Medical specialist in Internal Medicine and Nephrology

Guillermo Rosa Diez, University of Buenos Aires, Italian Hospital headquarters, City of Buenos Aires, Argentina

Specialist in Nephrology and Internal Environment, Master in Clinical Effectiveness (UBA), Doctor in Health Sciences (University of the Italian Hospital of Buenos Aires), Director of the Nephrology Specialist Course

Sonia Butto, Churruca Visca Hospital, City of Buenos Aires, Argentina

Medical specialist in Internal Medicine and Nephrology

Claudio González, Austral University, City of Buenos Aires, Argentina

Professor, Professor of Pharmacology, University Institute Center for Medical Education and Clinical Research "Norberto Quirno" (CEMIC), Director of the Master's Degree in Diabetes

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Published

2024-05-02

How to Cite

Papaginovic, M., Diez, G. R., Butto, S., & González, C. (2024). CHAPTER 9: NEPHROTOXICITY BY DRUGS. Journal of the Argentine Society of Diabetes, 58(2Sup), 54–62. https://doi.org/10.47196/diab.v58i2Sup.792

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Vol. 58 No. 2Sup (2024): May-August

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