Maternal glycemia of first trimester of pregnancy and gestational diabetes

Authors

  • María Cristina Faingold Cardiovascular Institute of Buenos Aires, Autonomous City of Buenos Aires, Argentina

DOI:

https://doi.org/10.47196/diab.v55i3.220

Keywords:

gestational diabetes, pregnancy, first trimester fasting blood glucose, macrosomia

Abstract

Gestational diabetes (GD) is characterized by a variety of metabolic changes ranging from physiological to pathophysiological. For many years the focus of research was on hyperglycemia. However, as detailed in the work published in this edition by Argerich et al .: “Maternal blood glucose in the first trimester of pregnancy and the probability of suffering from gestational diabetes. Categorization according to pre-pregnancy body mass index ”, there are other mechanisms that determine the probable complications of this entity, such as lipid alterations and body mass index (BMI) prior to pregnancy, as well as weight gain throughout it. However, there is no consensus regarding its diagnosis, nor in relation to the therapeutic goals. There is a general agreement on the objective to be achieved, which is: to try to achieve "normality". So the questions are: what is that normality? What are the lipid and protein goals in a pregnancy complicated by gestational diabetes?

Author Biography

María Cristina Faingold, Cardiovascular Institute of Buenos Aires, Autonomous City of Buenos Aires, Argentina

Medical Head of the Endocrinology Service, Dr. César Milstein Healthcare Unit; Staff Physician

References

I. Metzger BE, Lowe LP, Dyer AR, et al.; HAPO Study Cooperative Research Group. Hyperglycemia and adverse pregnancy outcomes. N Engl JMed 2008; 358:1991.

II. Lowe WL Jr, Scholtens DM, Kuang A, Linder B, Lawrence JM, Lebenthal Y, McCance D, Hamilton J, Nodzenski M, Talbot O, Brickman WJ, Clayton P, Ma RC, Tam WH, Dyer AR, Catalano PM, Lowe LP, Metzger BE; HAPO Follow-up Study Cooperative Research Group. Hyperglycemia and Adverse Pregnancy Outcome Follow-up Study (HAPO FUS): Maternal gestational diabetes mellitus and childhood glucose metabolism. Diabetes Care 2019 Mar; 42(3):372-380. DOI: 10.2337/dc18-1646.

III. Encuesta Nacional de Factores de Riesgo. Argentina. Informes 2005-2009-2013-2018. Acceso: 18/7/2019. Disponible en http://www.msal.gob.ar/ent/index.php/vigilancia/publicaciones/encuestas-poblacionales.

IV. Barbour LA, Hernández TL. Maternal non-glycemic contributors to fetal growth in obesity and gestational diabetes: spotlight on lipids. Curr Diab Rep 2018; 18:37. DOI: 10.1007/s11892-018-1008-2.

V. Sesmilo G, Prats P, García S, et al. First-trimester fasting glycemia as a predictor of gestational diabetes (GDM) and adverse pregnancy outcomes. Acta Diabetol 2020; 57(6):697-703. DOI: 10.1007/s00592-019-01474-8.

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Published

2021-09-01

How to Cite

Faingold, M. C. (2021). Maternal glycemia of first trimester of pregnancy and gestational diabetes. Journal of the Argentine Society of Diabetes, 55(3), 75–76. https://doi.org/10.47196/diab.v55i3.220

Issue

Vol. 55 No. 3 (2021): September/December 2021

Section

Editorial

License

Copyright (c) 2021 on behalf of the authors. Reproduction rights: Argentine Diabetes Society.

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

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