6 voices in 10 minutes: Kidney failure
DOI:
https://doi.org/10.47196/diab.v54i3Sup.289Keywords:
diabetes, chronic kidney disease, treatmentAbstract
6 voices in 10 minutes: Update on chronic complications
Kidney failure
Diabetes mellitus (DM) is the leading cause of chronic kidney disease (CKD). About 20-40% of patients with DM develop kidney disease due to this metabolic disorder, which increases the cardiovascular risk and can progress to a stage that requires dialysis or kidney transplantation. CKD typically develops after diabetes duration of 10 years in T1D patients and it is present in around 3% of T2D patients at diagnosis.
CKD is defined as the presence of elevated urinary albumin excretion (urinary albumin/creatinine ratio -ACR ≥30 mg/g-) and estimated glomerular filtration rate (eGFR) of <60 ml/min/1.73 m2, or both, during three months or more. This is known as chronic kidney disease. At least once a year, assess ACR and eGFR in patients with T1D with duration of ≥5 years and in all patients with T2D regardless of treatment. Patients with ACR >30 mg/g and/or an eGFR <60 ml/min/1.73 m2 should be monitored twice annually to guide therapy.
References
-1- KDIGO. Clinical Practice Guideline on Diabetes Management in Chronic Kidney Disease (in press).
-2- American Diabetes Association. 11. Microvascular complications and foot care: Standards of Medical Care in Diabetes 2020. Diabetes Care 2020; 43(Suppl. 1):S135–S151.
-3- American Diabetes Association. 9. Pharmacologic approaches to glycemic treatment: Standards of Medical Care in Diabetes 2020. Diabetes Care 2020;43(Suppl. 1):S98–S110.
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