Symposium 17: The neuropathy
DOI:
https://doi.org/10.47196/diab.v56i3Sup.595Keywords:
neuropathyAbstract
Diabetic motor sensitive polyneuropathy (DSPN) is the most prevalent complication, affecting about a third of people with type 1 and 2 diabetes, the number increases if all the different types of diabetes neuropathies are considered, being in particular, that DSPN represents considerable morbidity, a higher risk of mortality, a reduced quality of life as a result of sensitive alterations, especially pain, motor, visceral and an increase in health care costs as a result, in particular, of neuropathic pain and foot ulcers. Painful DSPN is found in 13-26%, while up to 50% of patients with NPCD can be asymptomatic.
Unfortunately, DSPN is still inadequately diagnosed, very late and treated incompletely. Currently, with the recommended diagnostic methodology to detect diabetic neuropathy and its possible phenotypes, it is already possible to establish in the daily clinic, the incipient dysfunctions of neuronal receptors (Paccini, Krausse, Libres, etc.), with their corresponding nerve fibers Beta (myelinized), Delta type I, type II (Neuropathic symptoms may be absent or present, typical ones include pain, paraesthesia and numbness, particularly in the feet and calves, bearing in mind that the predominant sign is the deficit of the alarm system "Nocceptual pain", they are usually accompanied by symptoms and / or signs of autonomic visceral dysfunctions.
References
I. Consensus statement: Report and recommendations of the San Antonio conference on diabetic neuropathy. American Diabetes Association American Academy of Neurology. Diabetes Care 1988;11:592-7.
II. Ponirakis G, Odriozola A, Malik RA. Nerve check for the detection of sensory loss and neuropathic pain in diabetes. Diabetes Technol Ther 2016 Dec;18(12):800-805.
III. American Diabetes Association. Microvascular complications and foot care: Standards of Medical Care in Diabetes-2020. Diabetes Care 2020; 43:S135–51.
IV. Rosenberger DC, Rolf‑Detlef AW. Challenges of neuropathic pain: focus on diabetic neuropathy. Journal of Neural Transmission 2020;127:589.
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