The importance of contributing to the diagnosis in complex diseases
DOI:
https://doi.org/10.47196/diab.v54i1.173Keywords:
diabetes, diagnosis, immunoassayAbstract
Diabetes is a heterogeneous syndrome in which various pathogenic and phenotypic expressions coexist that have a common feature of a state of chronic hyperglycemia. Two main etiological subtypes have been classically described: type 1 diabetes mellitus (DM1), characterized by autoimmune destruction of β cells and the consequent insulin deficiency, and type 2 diabetes mellitus (DM2), associated with insulin resistance and relative secretory deficiency. insulin At present it is recognized that this subdivision is a gross oversimplification and that it describes very little the pathogenic mechanisms and their clinical manifestations, and how they can be modified by genetic and environmental factors.
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