Opinions and recommendations of the Argentine Diabetes Society. Hemoglobin A1c

Authors

  • María del Carmen Maselli Faculty of Medicine, University of Buenos Aires (UBA), Autonomous City of Buenos Aires, Argentina
  • Isabel Llanos Faculty of Medicine, National University of the Northeast (UNNE), Hospital A.I. de Llano, Corrientes, Argentina
  • Carla Lucarelli Association of High Complexity Laboratories (ALAC), Bahía Blanca, Province of Buenos Aires, Argentina
  • Cecilia Fenili "Norberto Quirno" Medical Education and Clinical Research Center (ProgBA-CEMIC), Autonomous City of Buenos Aires, Argentina
  • Gabriela Ruibal T. Álvarez Hospital, Autonomous City of Buenos Aires, Argentina
  • Silvina Valdez Faculty of Pharmacy and Biochemistry, University of Buenos Aires (UBA), and Institute of Humoral Immunity Studies, Prof. R. Margni (IDEHU), UBA- National Council for Scientific and Technical Research (CONICET), Autonomous City of Buenos Aires, Argentina

DOI:

https://doi.org/10.47196/diab.v57i1.677

Keywords:

hemoglobin A1c, diagnostic, methods, standardization, recommendations

Abstract

The standardization of hemoglobin A1c (HbA1c) allowed in some countries its use for the diagnosis of diabetes mellitus (DM) and prediabetes, in addition to its use in the follow-up of patients with DM. It is important to highlight that it is an indirect measurement of the glycemic average during the half-life of the erythrocyte, and may be affected by non-glycemic variables, as well as by analytical interferences depending on the methodology used for its determination.

The recommendations and considerations to take into account for the determination of HbA1c when it is used as a diagnostic criterion for diabetes are described below. In addition, it is important to emphasize that it is essential that the HbA1c measurement be performed with certified and standardized methods to the Diabetes Control and Complications Trial (DCCT) results.

Author Biographies

María del Carmen Maselli, Faculty of Medicine, University of Buenos Aires (UBA), Autonomous City of Buenos Aires, Argentina

Former Biochemist and Researcher at the Hospital de Clínicas J. F. de San Martín Laboratory, University of Buenos Aires (UBA); Former Faculty of Pharmacy and Biochemistry, Argentine Diabetes Society (SAD)

Isabel Llanos, Faculty of Medicine, National University of the Northeast (UNNE), Hospital A.I. de Llano, Corrientes, Argentina

Chair of Biochemistry, Argentine Diabetes Society (SAD)

Carla Lucarelli, Association of High Complexity Laboratories (ALAC), Bahía Blanca, Province of Buenos Aires, Argentina

Biochemistry

Cecilia Fenili, "Norberto Quirno" Medical Education and Clinical Research Center (ProgBA-CEMIC), Autonomous City of Buenos Aires, Argentina

International Program for External Quality Assurance in Clinical Analysis

Silvina Valdez, Faculty of Pharmacy and Biochemistry, University of Buenos Aires (UBA), and Institute of Humoral Immunity Studies, Prof. R. Margni (IDEHU), UBA- National Council for Scientific and Technical Research (CONICET), Autonomous City of Buenos Aires, Argentina

Chair of Immunology, Argentine Diabetes Society (SAD)

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Published

2023-04-01

How to Cite

Maselli, M. del C., Llanos, I., Lucarelli, C., Fenili, C., Ruibal, G., & Valdez, S. (2023). Opinions and recommendations of the Argentine Diabetes Society. Hemoglobin A1c. Journal of the Argentine Society of Diabetes, 57(1), 20–23. https://doi.org/10.47196/diab.v57i1.677

Issue

Vol. 57 No. 1 (2023): January/April 2023

Section

Recommendations

License

Copyright (c) 2023 on behalf of the authors. Reproduction rights: Argentine Diabetes Society

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This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

Dirección Nacional de Derecho de Autor, Exp. N° 5.333.129. Instituto Nacional de la Propiedad Industrial, Marca «Revista de la Sociedad Argentina de Diabetes - Asociación Civil» N° de concesión 2.605.405 y N° de disposición 1.404/13.

La Revista de la SAD está licenciada bajo Licencia Creative Commons Atribución – No Comercial – Sin Obra Derivada 4.0 Internacional.

Por otra parte, la Revista SAD permite que los autores mantengan los derechos de autor sin restricciones.

 

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