P24 Hypoglycemia: prevalence and characterization in adult patients with type 1 and type 2 diabetes in the Comahue region

Authors

  • Liliana Alba Rocío Frias Argentine Diabetes Society, Autonomous City of Buenos Aires, Argentina
  • Danila Re Argentine Diabetes Society, Autonomous City of Buenos Aires, Argentina
  • Judith Bendahan Argentine Diabetes Society, Autonomous City of Buenos Aires, Argentina
  • Mariela Isabel Echenique Argentine Diabetes Society, Autonomous City of Buenos Aires, Argentina
  • Daniela Recalde Argentine Diabetes Society, Autonomous City of Buenos Aires, Argentina
  • Diego Botta Argentine Diabetes Society, Autonomous City of Buenos Aires, Argentina
  • Gabriela Silvana Illuminati Argentine Diabetes Society, Autonomous City of Buenos Aires, Argentina
  • Arturo López Rivera Argentine Diabetes Society, Autonomous City of Buenos Aires, Argentina
  • Diana Silvina González Argentine Diabetes Society, Autonomous City of Buenos Aires, Argentina
  • Ana Paula Devalle Argentine Diabetes Society, Autonomous City of Buenos Aires, Argentina
  • Matías Facundo Arias Argentine Diabetes Society, Autonomous City of Buenos Aires, Argentina
  • Nadia Mariel Bello Argentine Diabetes Society, Autonomous City of Buenos Aires, Argentina
  • Ramón Diego Carulla Argentine Diabetes Society, Autonomous City of Buenos Aires, Argentina
  • Carina Olga Coronel Argentine Diabetes Society, Autonomous City of Buenos Aires, Argentina
  • Carola Guzmán Campagnolli Argentine Diabetes Society, Autonomous City of Buenos Aires, Argentina
  • María Cristina Luaces Argentine Diabetes Society, Autonomous City of Buenos Aires, Argentina
  • María Lorena González López Argentine Diabetes Society, Autonomous City of Buenos Aires, Argentina
  • María del Rosario Puente Olivera Argentine Diabetes Society, Autonomous City of Buenos Aires, Argentina
  • Diego Adolfo Romanos Argentine Diabetes Society, Autonomous City of Buenos Aires, Argentina
  • Claudia Adriana Rodríguez Argentine Diabetes Society, Autonomous City of Buenos Aires, Argentina

DOI:

https://doi.org/10.47196/diab.v54i3Sup.408

Keywords:

hipoglucemia, adults, type 1 and 2 diabetes

Abstract

Introduction: hypoglycemia is a common adverse effect of diabetes treatment and is considered the major limiting factor in treatment. Addressing this issue is very important both in the office and in research.

Objectives: Asses the prevalence of any hypoglycemic event in adult patients with diabetes in the Comahue region and characterize them according to severity level (1,2y3) -D escribe the relationship between the prevalence of any event of the different hypoglycemic levels with sex, age, hbA1c, type of diabetes, duration of diabetes (years), type of treatment and complications associated with diabetes.

Materials and methods: Observational, multicenter, cross-sectional study, carried out between May and July 2020 in the Comahue Chapter of SAD. Patients with diabetes diagnosis aged >18 years were randomly surveyed.

Results: 452 patients answered the questionnaire (T1D: 18.1% and T2D: 78.8%). Mean age: 53.8 years Sex: male 51.1%. The mean duration of diabetes was 11.16 years. The mean HbA1c was 7.75%. The prevalence of any hypoglycemic event was 41%. In T1D it was 85.3% and 30.6% in T2D. In patients with T1D the prevalence for non-severe hypoglycemia, level 1, level 2, severe and nocturnal hypoglycemia was 82.9%, 80.4%, 31.7%, 23.1% and 51.2% respectively. Patients with T2D had a prevalence of 26.4%, 24.1%, 5.3%, 8.4% and 22.4% for non-severe hypoglycemia, level 1, level 2, severe and nocturnal respectively. Patients with non-severe, severe, and nocturnal hypoglycemia
had more neuropathy, duration of diabetes, years with insulin, insulin u/kg, and fear of hypoglycemia. Patients with non-severe hypoglycemia also had more retinopathy and use of CGM. Patients with severe and nocturnal hypoglycemia also had a higher prevalence of insulin therapy. Regarding the prevalence of hypoglycemia in relation to the type of treatment: with insulin therapy: 52.4% and without insulin therapy: 16.6%. When we analyze the prevalence by level of hypoglycemia in those with insulin therapy was: 49.5%, 12.7%, 37.4% for non severe, severe and nocturnal hypoglycemia respectively. In patients without insulin was: 9.7%, 6.9%, 8.3% for non-severe, severe and nocturnal hypoglycemia respectively.

Conclusions: The prevalence of any hypoglycemic event in Comahue Chapter-SAD was high in the analyzed population. The events in our patients with T1D are similar to those reported in local studies. Associated factors were related to the years of diabetes, dose and time of insulin therapy, microvascular complications, fear of hypoglycemia and the use of CGM. Strategies should be sought to improve glycemic control and avoid the potential hypoglycemic risks.

Author Biographies

Mariela Isabel Echenique, Argentine Diabetes Society, Autonomous City of Buenos Aires, Argentina

Staff doctor

Diego Botta, Argentine Diabetes Society, Autonomous City of Buenos Aires, Argentina

Diabetologist Doctor

Gabriela Silvana Illuminati, Argentine Diabetes Society, Autonomous City of Buenos Aires, Argentina

Physician, specialist in Internal Medicine

Arturo López Rivera, Argentine Diabetes Society, Autonomous City of Buenos Aires, Argentina

Internal Medicine Specialist and Master in Diabetes

Diana Silvina González, Argentine Diabetes Society, Autonomous City of Buenos Aires, Argentina

Nutrition and Childhood Diabetes Specialist

Ramón Diego Carulla, Argentine Diabetes Society, Autonomous City of Buenos Aires, Argentina

Specialist in General Medicine and Master in Diabetes

Published

2023-01-10

How to Cite

Frias, L. A. R., Re, D., Bendahan, J., Echenique, M. I., Recalde, D., Botta, D., Illuminati, G. S., López Rivera, A., González, D. S., Devalle, A. P., Arias, M. F., Bello, N. M., Carulla, R. D., Coronel, C. O., Guzmán Campagnolli, C., Luaces, M. C., González López, M. L., Puente Olivera, M. del R., Romanos, D. A., & Rodríguez, C. A. (2023). P24 Hypoglycemia: prevalence and characterization in adult patients with type 1 and type 2 diabetes in the Comahue region. Journal of the Argentine Society of Diabetes, 54(3Sup), 129–129. https://doi.org/10.47196/diab.v54i3Sup.408

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