Symposium 3: Impaired fasting glycemia: is it time to modify the cut-off value adopted by Argentina?

Authors

  • Víctor Commendatore National University of the Northeast (UNNE), Paraná, Entre Ríos, Argentina

DOI:

https://doi.org/10.47196/diab.v56i3Sup.494

Keywords:

prediabetes, HbA1c, glycosylated hemoglobin, fasting blood glucose, normal blood glucose

Abstract

At the end of the last century, in 1997, an International Committee of Experts convened by the American Diabetes Association (ADA) reassessed the classification and diagnostic criteria for diabetes mellitus (DM)1 defining, for the first time, the category called Impaired Fasting Glycemia (IFG), establishing its range between ≥110 mg/dL and <126 mg/dL, with the intention of establishing it as analogous to Impaired Glucose Tolerance (IGT), previously defined in a range of ≥140 and <200 mg/dL at 120 minutes of the Oral Glucose Tolerance Test (OGTT). Very shortly after, the World Health Organization (WHO) adopted much of what was resolved by the ADA, but advising that those with IFG undergo an OGTT to rule out or confirm the presence of IGT or DM2.

Later, at the beginning of this century, the ADA again brought together its experts to reevaluate what was previously defined and they decided, based on the new evidence regarding progression to DM and the appearance of macroangiopathic complications, to redefine the lower limit of IFG adopting 100 mg/dL3.

Author Biography

Víctor Commendatore, National University of the Northeast (UNNE), Paraná, Entre Ríos, Argentina

Endocrinologist

References

I. Report of the Expert Committee on the Diagnosis and Classification of Diabetes Mellitus. Diabetes Care. 1997 Jul;20(7):1183-97. doi: 10.2337/diacare.20.7.1183. PMID: 9203460.

II. World Health Organization. Definition, diagnosis and classification of diabetes mellitus and its complications: Report of a WHO Consultation. Part 1: Diagnosis and Classification of Diabetes Mellitus. Geneva, World Health Org., 1999.

III. Genuth S, Alberti KG, Bennett P, Buse J, et al.; Expert Committee on the Diagnosis and Classification of Diabetes Mellitus. Follow-up report on the diagnosis of diabetes mellitus. Diabetes Care. 2003 Nov;26(11):3160-7. doi: 10.2337/diacare.26.11.3160. PMID: 14578255.

IV. Consenso Sociedad de Diabetología y Nutrición del Uruguay-Sociedad Argentina de Diabetes. Convergencias, divergencias, variabilidad, puntos de corte e indicación de la glucemia de ayuno, la hemoglobina glucosilada e insulinemia. Arch Med Interna 2010; XXXII (2-3): 41-49 © Prensa Médica Latinoamericana. 2010 ISSN 0250-3816. Disponible en file:///D:/Users/victor/Downloads/v32n2-3a05.pdf

V. Faerch K, Borch-Johnsen K, Holst JJ, Vaag A. Pathophysiology and aetiology of impaired fasting glycaemia and impaired glucose tolerance: does it matter for prevention and treatment of type 2 diabetes? Diabetologia. 2009 Sep;52(9):1714-23. doi: 10.1007/s00125-009-1443-3. Epub 2009 Jul 10. PMID: 19590846.

VI. American Diabetes Association Professional Practice Committee; Draznin B, Aroda VR, Bakris G, Benson G, Brown FM, Freeman R, Green J, Huang E, Isaacs D, Kahan S, Leon J, Lyons SK, Peters AL, Prahalad P, Reusch JEB, Young-Hyman D, Das S, Kosiborod M. 2. Classification and Diagnosis of Diabetes: Standards of Medical Care in Diabetes-2022. Diabetes Care. 2022 Jan 1;45(Supplement_1):S17-S38. doi: 10.2337/dc22-S002. PMID: 34964875.

VII. Atlas de la Diabetes de la FID / Novena edición 2019.

VIII. Alberti KG, Zimmet PZ. Definition, diagnosis and classification of diabetes mellitus and its complications. Part 1: diagnosis and classification of diabetes mellitus provisional report of a WHO consultation. Diabet Med. 1998 Jul;15(7):539-53. doi: 10.1002/(SICI)1096-9136(199807)15:7<539:AID-DIA668>3.0.CO;2-S. PMID: 9686693.

IX. World Health Organization. Screening for type 2 diabetes. Report of a World Health Organization and International Diabetes Federation meeting. WHO/NMH/MNC/03.1 Geneva: WHO Department of Noncommunicable Disease Management. 2003

X. Shaw JE, Zimmet PZ, Hodge AM, de Courten M, Dowse GK, Chitson P, Tuomilehto J, Alberti KG. Impaired fasting glucose: how low should it go? Diabetes Care 2000 Jan;23(1):34-9. doi: 10.2337/diacare.23.1.34.

XI. DECODE Study Group, European Diabetes Epidemiology Group. Is the current definition for diabetes relevant to mortality risk from all causes and cardiovascular and noncardiovascular diseases? Diabetes Care 2003 Mar;26(3):688-96. doi: 10.2337/diacare.26.3.688.

XII. Huang Y, Cai X, Mai W, Li M, Hu Y. Association between prediabetes and risk of cardiovascular disease and all cause mortality: systematic review and meta-analysis. BMJ. 2016 Nov 23;355:i5953. doi: 10.1136/bmj.i5953.

XIII. Wong TY, Liew G, Tapp RJ, Schmidt MI, Wang JJ, Mitchell P, Klein R, Klein BE, Zimmet P, Shaw J. Relation between fasting glucose and retinopathy for diagnosis of diabetes: three population-based cross-sectional studies. Lancet. 2008 Mar 1;371(9614):736-43. doi: 10.1016/S0140-6736(08)60343-8. Erratum in: Lancet 2008 May 31;371(9627):1838.

XIV. Bortheiry AL, Malerbi DA, Franco LJ. The ROC curve in the evaluation of fasting capillary blood glucose as a screening test for diabetes and IGT. Diabetes Care 1994 Nov;17(11):1269-72. doi: 10.2337/diacare.17.11.1269.

XV. Chaila MZ y col. Glucemia en ayunas entre 100 y 109 mg/dL versus prediabetes según hemoglobina glicosilada. Revista de la Sociedad Argentina de Diabetes Vol. 56 Nº 2 Mayo-agosto de 2022:52-57.

Published

2022-09-01

How to Cite

Commendatore, V. (2022). Symposium 3: Impaired fasting glycemia: is it time to modify the cut-off value adopted by Argentina?. Journal of the Argentine Society of Diabetes, 56(3Sup), 9–9. https://doi.org/10.47196/diab.v56i3Sup.494

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