Symposium 6: Prevention and treatment

Authors

  • Alejandro Daín National University of Córdoba (UNC), Córdoba, Argentina

DOI:

https://doi.org/10.47196/diab.v56i3Sup.512

Keywords:

diabetes mellitus, prevention

Abstract

The concept of variability in hormonal homeostasis has been well known for a long time, we have various examples in biological models of fluctuations or oscillations in hormone concentrations or their final effectors. Glycemic variability is a component of glucose homeostasis in conjunction with its hormonal and non-hormonal regulators. The GV is a measure of dispersion related to the standard deviation. When these dispersions or oscillations overcome homeostatic control barriers, they can cause pathophysiological alterations with clinical consequences, increasing the risk of vascular and neurocognitive complications, among others.

To better understand this concept, we can compare it to a roller coaster and its many curves. The exposure time (duration of the trip) is correlated with the mean or average value, while the ups and downs with their dispersion or standard deviation. The result of dividing the DS over the mean x 100 gives us the value of VG.

Author Biography

Alejandro Daín, National University of Córdoba (UNC), Córdoba, Argentina

Doctor of Medicine and Surgery; University Professor, National University of Cordoba (UNC); Specialist in Internal Medicine, Diabetes and Clinical Nutrition; Diabetes Expert

References

I. Zhou Z, Sun B, Huang S, Zhu C, Bian M. Glycemic variability: adverse clinical outcomes and how to improve it? Cardiovasc Diabetol 2020;19(1):102.

II. Kapłan C, Kalemba A, Krok M, Krzych L. Effect of treatment and nutrition on glycemic variability in critically Ill patients. Int J Environ Res Public Health 2022 Apr 13;19(8):4717.

III. Kusunoki Y, Konishi K, Tsunoda T, Koyama H. Significance of glycemic variability in diabetes mellitus. Intern Med 2022;61(3):281-290.

IV. Suh S, Kim JH. Glycemic variability: how do we measure it and why is it important? Diabetes Metab J 2015;39(4):273-282.

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Published

2022-09-01

How to Cite

Daín, A. (2022). Symposium 6: Prevention and treatment. Journal of the Argentine Society of Diabetes, 56(3Sup), 21–21. https://doi.org/10.47196/diab.v56i3Sup.512

Issue

Vol. 56 No. 3Sup (2022): September/December 2022

Section

Symposium Part 2

License

Copyright (c) 2022 on behalf of the authors. Reproduction rights: Argentine Diabetes Society

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

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